nar/gkw124

Recombinant Human PCNP Protein Summary

    Description
    A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-178 of Human PCNP

    Source: E.coli

    Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMADGKA GDEKPEKSQR AGAAGGPEEE AEKPVKTKTV SSSNGGESSS RSAEKRSAEE EAADLPTKPT KISKFGFAIG SQTTKKASAI SIKLGSSKPK ETVPTLAPKT LSVAAAFNED EDSEPEEMPP EAKMRMKNIG RDTPTSAGPN SFNKGKHGFS DNQKLWERNI KSHLGNVHDQ DN

    Source
    E. coli
    Protein/Peptide Type
    Recombinant Protein
    Gene
    PCNP
    Purity
    >95% pure by SDS-PAGE

Applications/Dilutions

    Theoretical MW
    21.5 kDa.
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol
    Preservative
    No Preservative
    Concentration
    1 mg/ml
    Purity
    >95% pure by SDS-PAGE

Alternate Names for Recombinant Human PCNP Protein

      DKFZp781I24156
      PEST proteolytic signal containing nuclear protein
      PEST proteolytic signal-containing nuclear protein
      PEST-containing nuclear protein

Background

PCNP (PEST proteolytic signal containing nuclear protein) is a nuclear protein implied to play a role in cell cycle regulation and tumorigenesis. This protein is ubiquitinated post-translationally by NIRF, an ubiquitin ligase. PCNP exsists as three isoforms produced by alternative splicing events and may be involved in cell cycle regulation. Recombinant human PCNP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

product targets : TAK8 inhibitors

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