Recombinant Human NUDT3 Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-172 of Human NUDT3
Source: E.coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MMKLKSNQTR TYDGDGYKKR AACLCFRSES EEEVLLVSSS RHPDRWIVPG GGMEPEEEPS VAAVREVCEE AGVKGTLGRL VGIFENQERK HRTYVYVLIV TEVLEDWEDS VNIGRKREWF KIEDAIKVLQ YHKPVQASYF ETLRQGYSAN NGTPVVATTY SVSAQSSMSG IR
E. coli
Recombinant Protein
NUDT3
>95% pure by SDS-PAGE
Applications/Dilutions
21.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol
No Preservative
0.5 mg/ml
>95% pure by SDS-PAGE
Alternate Names for Recombinant Human NUDT3 Protein
- Diadenosine 5-5-P1
- diphosphoinositol polyphosphate phosphohydrolase 1
- DIPP-1
- DIPPDIPP1
- EC 3.6.1.-
- EC 3.6.1.52
- Nucleoside diphosphate-linked moiety X motif 3
- nudix (nucleoside diphosphate linked moiety X)-type motif 3
- Nudix motif 3
- P6-hexaphosphate hydrolase 1
Background
NUDT3, also known as DIPP, DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1), is a 172 amino acid cytoplasmic protein belonging to the nudix hydrolase family and DIPP subfamily. NUDT3 acts as a negative regulator of the ERK 1/2 pathway and hydrolyzes 5-phosphoribose 1-diphosphate. NUDT3 exists as a monomer and binds magnesium as a cofactor. Also NUDT3 is widely expressed but found at highest levels in liver, pancreas, brain and heart. Recombinant human NUDT3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　Adenosine Kinase inhibitors