Recombinant Human MP1/MAP2K1IP1 Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-124 of Human MP1/MAP2K1IP1
Source: E.coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MADDLKRFLY KKLPSVEGLH AIVVSDRDGV PVIKVANDNA PEHALRPGFL STFALATDQG SKLGLSKNKS IICYYNTYQV VQFNRLPLVV SFIASSSANT GLIVSLEKEL APLFEELRQV VEVS
E. coli
Recombinant Protein
LAMTOR3
>95% pure by SDS-PAGE
Applications/Dilutions
15.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 5mM DTT, 100mM NaCl
No Preservative
0.5 mg/ml
>95% pure by SDS-PAGE
Alternate Names for Recombinant Human MP1/MAP2K1IP1 Protein
- LAMTOR3
- Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3
- late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
- MAP2K1IP1
- Mapbp
- MAPK scaffold protein 1
- MAPKSP1
- MEK binding partner 1
- MEK partner 1
- MEK-binding partner 1
- mitogen-activated protein kinase kinase 1 interacting protein 1
- Mitogen-activated protein kinase kinase 1-interacting protein 1
- Mitogen-activated protein kinase scaffold protein 1
- MP1
- PRO0633
- Ragulator3
Background
MAPKSP1 (Mitogen-activated protein kinase scaffold protein 1) is a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Recombinant human MAPKSP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　Ribosomal S13 Kinase (RSK) inhibitors