Recombinant Human LSM1 Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-133 of Human LSM1
Source: E.coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MNYMPGTASL IEDIDKKHLV LLRDGRTLIG FLRSIDQFAN LVLHQTVERI HVGKKYGDIP RGIFVVRGEN VVLLGEIDLE KESDTPLQQV SIEEILEEQR VEQQTKLEAE KLKVQALKDR GLSIPRADTL DEY
E. coli
Recombinant Protein
LSM1
>95% pure by SDS-PAGE
Applications/Dilutions
17.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 10% glycerol, 0.1M NaCl
No Preservative
1 mg/ml
>95% pure by SDS-PAGE
Alternate Names for Recombinant Human LSM1 Protein
- Cancer-associated Sm-like
- CASMYJL124C
- LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
- Small nuclear ribonuclear CaSm
- U6 snRNA-associated Sm-like protein LSm1
Background
U6 snRNA-associated Sm-like protein LSm1, also known as LSM1 plays a role in replication-dependent histone mRNA degradation and binds specifically to the 3-terminal U-tract of U6 snRNA. LSM1 protein facilitates RNA protein interactions and structural changes that are required during ribosomal subunit assembly. LSM1 is naturally overexpressed in pancreatic cancer as well as in certain breast cancer cell lines. Recombinant human LSM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets : c-Myc inhibitors