journal.pntd.0004490

Recombinant Human GABARAPL1 Protein Summary

    Description
    A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-117 of Human GABARAPL1

    Source: E.coli

    Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MKFQYKEDHP FEYRKKEGEK IRKKYPDRVP VIVEKAPKAR VPDLDKRKYL VPSDLTVGQF YFLIRKRIHL RPEDALFFFV NNTIPPTSAT MGQLYEDNHE EDYFLYVAYS DESVYGK

    Source
    E. coli
    Protein/Peptide Type
    Recombinant Protein
    Gene
    GABARAPL1
    Purity
    >90%, by SDS-PAGE

Applications/Dilutions

    Theoretical MW
    16.2 kDa.
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    20mM Tris buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl
    Preservative
    No Preservative
    Concentration
    1 mg/ml
    Purity
    >90%, by SDS-PAGE

Alternate Names for Recombinant Human GABARAPL1 Protein

      APG8L
      APG8-LIKE
      ATG8
      ATG8B
      ATG8L
      Early estrogen-regulated protein
      GABA(A) receptor-associated protein like 1
      GABARAPL1
      gamma-aminobutyric acid receptor-associated protein-like 1
      GEC1
      GEC-1
      GEC1GABA(A) receptor-associated protein-like 1
      Glandular epithelial cell protein 1

Background

Gamma-aminobutyric acid (GABA) receptor-associated protein-like 1, also known as GABARAPL1, belongs to the MAP1 LC3 family. It increases cell surface expression of kappa type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Recombinant human GABARAPL1 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

product targets : Serotonin Transporter inhibitors

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