fpls.2016.00297

Recombinant Human FAM3C Protein Summary

    Description
    A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 25-227 of Human FAM3C

    Source: E.coli

    Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MQVFEIKMDA SLGNLFARSA LDTAARSTKP PRYKCGISKA CPEKHFAFKM ASGAANVVGP KICLEDNVLM SGVKNNVGRG INVALANGKT GEVLDTKYFD MWGGDVAPFI EFLKAIQDGT IVLMGTYDDG ATKLNDEARR LIADLGSTSI TNLGFRDNWV FCGGKGIKTK SPFEQHIKNN KDTNKYEGWP EVVEMEGCIP QKQD

    Source
    E. coli
    Protein/Peptide Type
    Recombinant Protein
    Gene
    FAM3C
    Purity
    >90%, by SDS-PAGE

Applications/Dilutions

    Theoretical MW
    24.5 kDa.
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 20% glycerol, 200mM NaCl
    Preservative
    No Preservative
    Concentration
    0.5 mg/ml
    Purity
    >90%, by SDS-PAGE

Alternate Names for Recombinant Human FAM3C Protein

      D6WSU176e
      FAM3C
      family with sequence similarity 3, member C
      GS3876
      ILEI
      ILEIInterleukin-like EMT inducer
      predicted osteoblast protein

Background

FAB3C belongs to the FAM3 family and contains a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells. Fam3c may be a downstream target gene for the Nkx5.1 transcription factor, and may thus be involved in cell differentiation and proliferation during inner ear embryogenesis. Also, it may be involved in retinal laminar formation and promotes epithelial to mesenchymal transition. Recombinant human FAM3C, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

product targets : Potassium Channel inhibitors

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