bmjopen-2015-008828

Recombinant Human Erythropoietin Protein Summary

    Description
    Recombinant bioactive protein containing 166 amino acids for Human Erythropoietin

    Source:CHO cells
    Amino Acid Sequence:(P01588)

    Preparation
    Method
    >98% SDS-PAGE
    Details of Functionality
    Determined by a cell proliferation assay using TF-1 cells. The expected ED50 for this effect is 0.8-1.0 ng/ml.
    Source
    CHO
    Protein/Peptide Type
    Biologically Active Protein
    Gene
    EPO
    Purity
    >95%, by SDS-PAGE
    Endotoxin Note
    <0.1 ng/ug

Applications/Dilutions

    Theoretical MW
    37 kDa.
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

    Storage
    Store at -20 to -80C. Avoid freeze-thaw cycles.
    Buffer
    lyophilized in sodium citrate buffer containing sodium chloride
    Concentration
    Lyoph
    Purity
    >95%, by SDS-PAGE
    Reconstitution Instructions
    Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1 to 1.0 mg/ml. This solution can then be diluted into other aqueous buffers containing a carrier protein (like 0.1% BSA) and stored in working aliquots at -20C to -80C for future use.

Alternate Names for Recombinant Human Erythropoietin Protein

      EP
      EPO
      epoetin
      Erythropoietin
      MGC138142
      MVCD2

Background

Recombinant Human Erythropoietin-alpha produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology is a single, polypeptide chain containing 165 amino acids and having a predicted molecular mass of 21 kDa and apparent glycosylated molecular mass of 30.4 kDa. EPO-alpha is purified by proprietary chromatographic techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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