Recombinant Human DPPIV/CD26 Protein Summary

ADABP
ADCP-2
ADCP2DPP IV
Adenosine deaminase complexing protein 2TP103
CD26 antigen
CD26
CD26T-cell activation antigen CD26
dipeptidyl peptidase 4
Dipeptidyl peptidase IV
dipeptidylpeptidase 4
dipeptidyl-peptidase 4
dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
DPP4
DPPIV
EC 3.4.14.5

DPP4 is a serine exopeptidase and complex enzyme that is expressed on the surface of most cell types as an intrinsic membrane glycoprotein that cleaves X-proline dipeptides from the N-terminus of polypeptides and plays a role in t-cell activation. DPP4 is associated with intracellular signal transduction, apoptosis and involved in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors, chemokines, neuro peptides. Furthermore, DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). DPP4 Human Recombinant is a single, glycosylated polypeptide chain containing 746 amino acids (aa 39-766) with a C-terminal His-tag and is purified using conventional chromatography techniques.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.