s16010004

Recombinant Human Cathepsin B Protein Summary

    Description
    Native Cathepsin B

    Source:Human liver
    Amino Acid Sequence:(P07858)

    Protein/Peptide Type
    Biologically Active Protein
    Gene
    CTSB
    Purity
    >95%, by SDS-PAGE

Applications/Dilutions

    Application Notes
    Unit Definition: >200 units/mg protein. One unit is defined as the amount of enzyme that hydrolyzes one nmol Z-Arg-Arg-AFC substrate per minute at 37C pH 6.0 with 10 mM DTT.
    Specific activity: 470 units/mg

Packaging, Storage & Formulations

    Storage
    Store at -20 to -80C. Avoid freeze-thaw cycles.
    Buffer
    Liquid solution containing 50 mM sodium acetate, pH 5.0, with 1 mM EDTA
    Concentration
    1 mg/ml
    Purity
    >95%, by SDS-PAGE

Alternate Names for Recombinant Human Cathepsin B Protein

      APP secretase
      APPS
      Cathepsin B
      Cathepsin B1
      CPSBamyloid precursor protein secretase
      CTSB
      cysteine protease
      EC 3.4.22
      EC 3.4.22.1

Background

Cathepsin B is a lysosomal cysteine protease. It is implicated in playing a role in protein degradation, arthritis, apoptosis, and cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

Quizartinib

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