Recombinant Human Calponin 1 Protein Summary
A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 1-297 of Human Calponin 1
Source: E.coli
Amino Acid Sequence: MSSAHFNRGP AYGLSAEVKN KLAQKYDHQR EQELREWIEG VTGRRIGNNF MDGLKDGIIL CEFINKLQPG SVKKINESTQ NWHQLENIGN FIKAITKYGV KPHDIFEAND LFENTNHTQV QSTLLALASM AKTKGNKVNV GVKYAEKQER KFEPGKLREG RNIIGLQMGT NKFASQQGMT AYGTRRHLYD PKLGTDQPLD QATISLQMGT NKGASQAGMT APGTKRQIFE PGLGMEHCDT LNVSLQMGSN KGASQRGMTV YGLPRQVYDP KYCLTPEYPE LGEPAHNHHA HNYYNSALEH HHHHH
E. coli
Recombinant Protein
CNN1
>90%, by SDS-PAGE
Applications/Dilutions
34.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.15M NaCl, 1mM DTT
No Preservative
1 mg/ml
>90%, by SDS-PAGE
Alternate Names for Recombinant Human Calponin 1 Protein
- Basic calponin
- Calponin 1
- calponin 1, basic, smooth muscle
- Calponin H1
- Calponin H1, smooth muscle
- calponins, basic
- CNN1
- Sm-Calp
- SMCC
- SMCCcalponin-1
Background
CNN1, also known as calponin-1, belongs to the calponin family. CNN1 is thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Recombinant human CNN1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　IRAK inhibitors