Recombinant Human CHMP2B Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-213 of Human CHMP2B
Source: E.coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACKV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKATISD EEIERQLKAL GVD
E. coli
Recombinant Protein
CHMP2B
>90%, by SDS-PAGE
Applications/Dilutions
26.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl
No Preservative
0.5 mg/ml
>90%, by SDS-PAGE
Alternate Names for Recombinant Human CHMP2B Protein
- charged multivesicular body protein 2b
- CHMP2.5
- CHMP2.5VPS2BVPS2-2
- CHMP2B
- chromatin modifying protein 2B
- Chromatin-modifying protein 2b
- DKFZP564O123
- DMT1
- hVps2-2
- Vacuolar protein sorting-associated protein 2-2
- vacuolar protein-sorting-associated protein 2-2
- VPS2 homolog B
- Vps2-2
- VPS2B
Background
CHMP2B belongs to the vacuolar sorting protein family. It is a component of the ESCRT-III complex. This complex is crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes. Recombinant human CHMP2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　Antifolate inhibitors