Recombinant Human AK3L1 Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-223 of Human AK3L1
Source: E.coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MASKLLRAVI LGPPGSGKGT VCQRIAQNFG LQHLSSGHFL RENIKASTEV GEMAKQYIEK SLLVPDHVIT RLMMSELENR RGQHWLLDGF PRTLGQAEAL DKICEVDLVI SLNIPFETLK DRLSRRWIHP PSGRVYNLDF NPPHVHGIDD VTGEPLVQQE DDKPEAVAAR LRQYKDVAKP VIELYKSRGV LHQFSGTETN KIWPYVYTLF SNKITPIQSK EAY
E. coli
Recombinant Protein
AK4
>90%, by SDS-PAGE
Applications/Dilutions
27.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl
No Preservative
1 mg/ml
>90%, by SDS-PAGE
Alternate Names for Recombinant Human AK3L1 Protein
- adenylate kinase 3
- adenylate kinase 3-like 1
- Adenylate kinase 3-like
- adenylate kinase 4
- AK3adenylate kinase isoenzyme 4, mitochondrial
- AK3L1
- AK3L2
- ATP-AMP transphosphorylase
- EC 2.7.4
- EC 2.7.4.3
- GTP:AMP phosphotransferase
- MGC166959
- mitochondrial adenylate kinase-3
- nucleoside-triphosphate-adenylate kinase
Background
AK4(adenylate kinase 4) is a member of the adenylate kinase family of enzymes. This protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Inherited mutations leading to AK4 deficiencies in erythrocytes have been implicated in hemolytic anemia. Recombinant human AK4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　Thymidylate Synthase inhibitors