Recombinant Human 4-1BB/TNFRSF9/CD137 Protein Summary
Recombinant bioactive protein containing 167 amino acids for Human 4-1BB/TNFRSF9/CD137
Source:E. coli
Amino Acid Sequence:(Q07011 )
Method
>98% SDS-PAGE
Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC. About 90% of inhibition was seen using a concentration of 1 ug for both 4-1BBL and 4-1BBR.
E. coli
Biologically Active Protein
TNFRSF9
>95%, by SDS-PAGE
<0.1 ng/ug
Applications/Dilutions
17.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at -20 to -80C. Avoid freeze-thaw cycles.
Lyophilized with no additives
Lyoph
>95%, by SDS-PAGE
Reconstitute in H2O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20C for future use.
Alternate Names for Recombinant Human 4-1BB/TNFRSF9/CD137 Protein
- 4-1BB ligand receptor
- 41BB
- 4-1BB
- CD137 antigen
- CD137
- CD137MGC2172
- CDw137
- FLJ43501
- ILA
- ILAhomolog of mouse 4-1BB
- induced by lymphocyte activation (ILA)
- interleukin-activated receptor, homolog of mouse Ly63
- receptor protein 4-1BB
- T cell antigen ILA
- T-cell antigen 4-1BB homolog
- T-cell antigen ILA
- TNFRSF9
- tumor necrosis factor receptor superfamily member 9
- tumor necrosis factor receptor superfamily, member 9
Background
Human 4-1BB Receptor (4-1BBR) is an inhibitor of 4-1BBL and can block 4-1BBL bioactivity. Recombinant human 4-1BBR is a 17.8 kDa protein containing 167 amino acid residues of extraCellular domain of 4-1BBR without signal peptide (Gene accession # NP_001552).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.