Rat TGF-beta 1 ELISA Kit Summary
31.3 – 2,000 pg/mL
8.0 pg/mL
100 uL (pretreated)
ELISA Kit
TGFB1
Applications/Dilutions
The rat TGF-beta1 ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of rat TGF-beta1
Reactivity Notes
Rat
Packaging, Storage & Formulations
Storage of components varies. See protocol for specific instructions.
Kit Components
- Streptavidin-HRP
- Substrat Solution (tetramethyl-benzidine)
- Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
- Rat TGF-beta1 Standard lyophilized, 4000 pg/ml upon reconstitution
- Stop Solution (1M Phosphoric acid)
- Adhesive Films
- Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to rat TGF-beta1
- Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
- Biotin-Conjugate anti-rat TGF-beta1 polyclonal antibody
Alternate Names for Rat TGF-beta 1 ELISA Kit
- CEDLAP
- DPD1
- latency-associated peptide
- TGFB
- TGFB1
- TGF-beta 1 protein
- TGFbeta 1
- TGF-beta 1
- TGFbeta
- TGF-beta-1
- transforming growth factor beta-1
- transforming growth factor, beta 1
Background
TGF-beta plays a critical role in cellular growth, development, differentiation, proliferation, extracellular matrix (ECM) synthesis and degradation, control of mesenchymal-epithelial interactions during embryogenesis, immune modulation, apoptosis, cell cycle progression, angiogenesis, adhesion and migration and leukocyte chemotaxis. It has both tumor suppressive and tumor promoting activities and is highly regulated at all levels. TGF-beta1 is the key mediator in the pathophysiology of tissue repair and human fibrogenesis: balance between production and degradation of type I collagen, and fibrosis and scarring in organ and tissue. TGF-beta1 promotes Treg cell differentiation resulting in IL-10/TGF-beta1 production and Th1 cell and Th2 cell suppression.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.