Rab3D Antibody Summary
Synthetic peptide corresponding to residues M(1) A S A S E P P A S P R D A A D Q N(18) of rat RAB3D.
Detects recombinant mouse rab 3D. This does not detect rab 3A, 3B, or 3C.
IgG
Polyclonal
Rabbit
RAB3D
Protein A purified
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Applications/Dilutions
- Western Blot 2.0 ug/ml
WB: Detects an approx. 29 kDa protein representing recombinant mouse Rab 3D.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
PBS
0.05% Sodium Azide
1 mg/ml
Protein A purified
Alternate Names for Rab3D Antibody
- D2-2
- GOVras-related protein Rab-3D
- RAB16glioblastoma overexpressed
- RAB3D, member RAS oncogene family
- RAD3DRab3D upregulated with myeloid differentiation
Background
Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 rab proteins that have been described in mammals. Rab 3D has been shown to be present, in part, in the tongue, pancreas, and liver.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.