RUNX2/CBFA1 Antibody Summary
RUNX2 (NP_004339, 251 a.a. – 350 a.a.) partial recombinant protein with GST tag. NPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQAGA
RUNX2 – runt-related transcription factor 2
IgG
Polyclonal
Mouse
RUNX2
Unpurified
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Applications/Dilutions
- Western Blot
- ELISA
The quality control of this antibody is limited to WB on the immunizing protein. It has been used for ELISA. Abnovas recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Whole antisera with 50% Glycerol
No Preservative
Unpurified
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for RUNX2/CBFA1 Antibody
- Acute myeloid leukemia 3 protein
- AML3CCD
- CBFA1
- CBFA1MGC120022
- Core-binding factor subunit alpha-1
- MGC120023
- PEA2-alpha A
- PEBP2A
- PEBP2A1CCD1
- PEBP2aA1
- PEBP2-alpha A
- runt domain, alpha subunit 1
- runt-related transcription factor 2
- RUNX2
- SL3/AKV core-binding factor alpha A subunit
- SL3-3 enhancer factor 1 alpha A subunit
Background
This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.