peerj.2059

RPB2 Antibody Summary

    Immunogen
    A synthetic peptide, which represented a portion of C-terminus of human DNA directed RNA polymerase II 140 kDa subunit encoded within exon 11.(LocusLink ID 5431).
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    POLR2B
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Western Blot 1:1000-1:5000
        Immunoprecipitation 2 – 5 ug/mg lysate
    Application Notes
    Uses: NB 100-334 may be used for Western Blot.. Suggested working dilutions: * Western Blot – 1:1,000-1:5,000 (ECL) Immunohisto/cytochemistry – Not Determined *The investigator should determine the optimal working dilution for a specific application.

Packaging, Storage & Formulations

    Storage
    Store at 4C. Do not freeze.
    Buffer
    Tris-Citrate/Phosphate (pH 7.0 – 8.0)
    Preservative
    0.09% Sodium Azide
    Concentration
    1 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for RPB2 Antibody

      DNA-directed RNA polymerase II subunit RPB2
      EC 2.7.7
      EC 2.7.7.6
      hRPB140
      hsRPB2
      POL2RB
      polymerase (RNA) II (DNA directed) polypeptide B (140kD)
      polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
      RNA polymerase II subunit 2
      RNA polymerase II subunit B2
      RNA polymerase II subunit2, RNA polymerase II second largest subunit

Background

It is suggested that Rpb2, a 140 kDa protein, plays a role is enhancing transcription from prostate specific antigen genes. These genes may be linked to prostate cancer progression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : JAK/STAT_Compound_Library inhibitors

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