j.jfoodeng.2015.10.019

ROR alpha/NR1F1 Antibody (784652) [Alexa Fluor® 594] Summary

    Immunogen
    E. coli-derived recombinant human ROR alpha /NR1F1
    Arg47-His163
    Accession # P35398
    Specificity
    Detects human ROR alpha /NR1F1 in direct ELISAs.
    Isotype
    IgG2b
    Clonality
    Monoclonal
    Host
    Mouse
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Applications/Dilutions

    Dilutions
        Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Store the unopened product at 2 – 8 °C. Do not use past expiration date.
    Buffer
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ROR alpha/NR1F1 Antibody (784652) [Alexa Fluor® 594]

      DKFZp686M2414
      MGC119326
      NR1F1
      NR1F1MGC119329
      nuclear receptor ROR-alpha
      Nuclear receptor RZR-alpha
      Nuclear receptor subfamily 1 group F member 1
      RAR-related orphan receptor A
      RAR-related orphan receptor alpha
      retinoic acid receptor-related orphan receptor alpha
      retinoid-related orphan receptor alpha
      Retinoid-related orphan receptor-alpha
      ROR alpha
      ROR1
      ROR2
      ROR3
      RORA
      RZRA
      RZR-ALPHA
      RZRAROR-alpha
      transcription factor RZR-alpha

Background

RORa (Retinoid-related Orphan Receptor alpha ) is a member of the NR1 nuclear hormone receptor family. ROR alpha is a DNA binding transcription factor, and can bind as a monomer or homodimer to hormone response elements to enhance expression.  Knockout mice implicate ROR alpha as being essential in the development of the cerebellum. It has also been reported to regulate lymphocyte development and play a role in Th17 differentiation. Human ROR alpha shares 99% amino sequence identity with mouse ROR alpha.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

HC-030042

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