RGR Antibody Summary
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human RGR.
Retinal G Protein-Coupled Receptor RPE
IgG
Polyclonal
Rabbit
RGR
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry-Paraffin 1:10-1:500
Reactivity Notes
Human
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified
Alternate Names for RGR Antibody
- retinal G protein coupled receptor
- RGR-opsin
- RP44
- RPE retinal G-protein coupled receptor
- RPE-retinal G protein-coupled receptor
Background
Retinal G protein-coupled receptor RPE, a member of the Opsin subfamily of GPCRs has been shown to be involved in retinitis pigmentosa. It preferentially binds all-trans retinal rather than 11-cis retinal, which is normally found in rhodopsin. RPE has two isoforms produced by alternative splicing. Retinal G protein-coupled receptor RPE has been reported to be expressed in the eye. ESTs have been isolated from normal human brain and eye libraries and from human brain and colon cancer libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.