Primate IL-2 ELISA Kit (Colorimetric) Summary
18.8-1,200 U/mL
9.1 U/mL
Sandwich ELISA
5.0%
7.0%
50 uL
ELISA Kit (Colorimetric)
IL2
Applications/Dilutions
This kit is an enzyme-linked immunosorbent assay for quantitative detection.
Reactivity Notes
Monkey
Packaging, Storage & Formulations
Storage of components varies. See protocol for specific instructions.
Kit Components
- Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to monkey IL-2
Alternate Names for Primate IL-2 ELISA Kit (Colorimetric)
- aldesleukin
- IL2
- IL-2
- IL-2lymphokine
- interleukin 2
- interleukin-2
- involved in regulation of T-cell clonal expansion
- T cell growth factor
- T-cell growth factor
- TCGF
Background
IL-2 plays a central role in the activation and proliferation of lymphocytes that have been primed by antigens. IL-2 plays a pivotal role in for the expansion of most T-cells, natural killer cells and B-cells during certain phases of their response. IL-2 is a 15 kDa glycoprotein encoded by a single gene located in the q26-28 region of human chromosome 4. The cDNA deduced polypeptide consists of 153 amino acids. Apart from its most important role to mediate antigen-specific T-lymphocyte proliferation, IL-2 modulates the expression of interferon gamma and major histocompatibility antigens, stimulates proliferation and differentiation of activated B-cells, augments natural killer cell activity and inhibits granulocyte-macrophage colony formation. IL-2 displays antitumoral effects, thus being used in cancer therapy. Monitoring of IL-2 levels in serum provides more detailed insights in several pathological situations such as cancer, infectious diseases, transplant rejection, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus and type I diabetes.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.