Plasminogen Antibody Summary
Chicken Plasminogen
Chicken Plasminogen and plasmin.
IgG
Polyclonal
Rabbit
PLG
Protein A purified
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Applications/Dilutions
- Western Blot 1-5 ug/ml
- ELISA 1:10000
Reactivity Notes
Reacts with chicken plasminogen.
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
50mM Sodium Phosphate (pH 6.6), 0.1M NaCl and 1mM EDTA
No Preservative
8.5 mg/ml
Protein A purified
Alternate Names for Plasminogen Antibody
- DKFZp779M0222
- EC 3.4.21
- EC 3.4.21.7
- plasmin
- Plasminogen
- Plg
Background
Plasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 to 200mg/l. Plasminogen is activated by tissue plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.