j.clinph.2015.04.075

Pepsinogen I Antibody (8003 (99/12)) Summary

    Immunogen
    Purified human pepsinogen 1.
    Localization
    Secreted
    Specificity
    NB100-62239 recognises human Pepsinogen I, a zymogen or proenzyme secreted by Chief cells in the stomach. It is cleaved to form pepsin both in an autocatalytic fashion and by pepsin itself. In humans there are two related forms of pepsin, Pepsinogen I (also known as pepsinogen A), and Pepsinogen II (also known as Pepsinogen B or progastricsin).
    Isotype
    IgG1
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    PGA3
    Purity
    Protein A purified
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Applications/Dilutions

    Dilutions
        ELISA 1:100-1:2000
        Immunohistochemistry-Paraffin
        Radioimmunoassay 1:100-1:2000

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.09% Sodium Azide
    Concentration
    0.5 mg/ml
    Purity
    Protein A purified

Alternate Names for Pepsinogen I Antibody (8003 (99/12))

      pepsinogen 3, group I (pepsinogen A)

Background

Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular weight of 42 kDa. Pepsinogen I is synthesized by gastric chief cells and mucous neck cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

PD168401

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