PLA2G3 Antibody Summary
Synthetic 16 amino acid peptide from internal region of human PLA2G3.
internal domain of human
Human PLA2G3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Mouse (94%), Rat (94%), Hamster (94%), Canine (94%), Primate (94%), Monkey (100%). Backed by our 100% Guarantee.
IgG
Polyclonal
Rabbit
PLA2G3
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry-Paraffin 10 ug/ml
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Elephant (88%), Panda (88%), Rabbit (88%), Bovine (81%), Equine (81%), Porcine (81%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.1% Sodium Azide
1 mg/ml
Immunogen affinity purified
Alternate Names for PLA2G3 Antibody
- EC 3.1.1.4
- GIII sPLA2
- GIII-SPLA2
- group 3 secretory phospholipase A2
- group III secreted phospholipase A2
- Group III secretory phospholipase A2
- Phosphatidylcholine 2-acylhydrolase 3
- phosphatidylcholine 2-acylhydrolase GIII
- phospholipase A2, group III
- SPLA2III
- sPLA2-III
Background
PLA2G3 (Human group III secreted phospholipase A2) belongs to a superfamily of intracellular and secreted enzymes that catalyze the hydrolysis of glycerophospholipids to release fatty acids and lysophospholipids. Human PLA2G3 has been shown to be a calcium dependent enzyme, consisting of a central group III sPLA2 domain flanked by unique N and C terminal domains that are proteolytically cleavedin most tissues. The sPLA2 domain is sufficient for catalytic activity. SPLA2-III is expressed in the microvascular endothelium of tissues with inflammation, ischemic injury and cancer.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.