j.exger.2015.11.011

PIB5PA Antibody Summary

    Immunogen
    Synthetic 15 amino acid peptide from N-terminus of human INPP5J / PIB5PA.
    Epitope
    N-terminal region of human.
    Specificity
    Human INPP5J / PIB5PA. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    INPP5J
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Immunohistochemistry-Paraffin 12 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (87%), Marmost (80%).

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.1% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for PIB5PA Antibody

      A
      inositol polyphosphate 5-phosphatase J
      inositol polyphosphate-5-phosphatase J
      phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
      PIPP

Background

Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. PIB5PA may be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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