s11999-015-4639-5

PDK-1 Antibody (3B7) Summary

    Immunogen
    PDK1 (AAH39158 203 a.a. – 302 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GGKGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQ
    Specificity
    PDK1 – pyruvate dehydrogenase kinase, isoenzyme 1
    Isotype
    IgG2b Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    PDK1
    Purity
    IgG purified
    Innovators Reward
    Test in a species/application not listed above to receive a full credit towards a future purchase.

    Learn about the Innovators Reward

Applications/Dilutions

    Dilutions
        ELISA
    Application Notes
    Antibody reactivity against recombinant protein on ELISA. GST alone used as a negative control.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PDK-1 Antibody (3B7)

      [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial
      EC 2.7.11
      EC 2.7.11.2
      mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1
      PDK1
      PDK-1
      PDPK1
      PKB kinase
      Pyruvate dehydrogenase kinase isoform 1
      pyruvate dehydrogenase kinase, isoenzyme 1
      pyruvate dehydrogenase kinase, isozyme 1

Background

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Vercirnon

Related Post