co.22.2592

PDE3A Antibody Summary

    Immunogen
    Synthetic 19 amino acid peptide from near N-terminus of human PDE3A.
    Epitope
    near N-terminus of human
    Specificity
    Human PDE3A. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except EDN3 (58%).
    Predicted Species
    Primate (94%), Monkey (94%). Backed by our 100% Guarantee.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    PDE3A
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Immunohistochemistry-Paraffin 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (94%).

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.1% Sodium Azide
    Concentration
    0.27 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for PDE3A Antibody

      CGI-PDE A
      CGI-PDE
      cGMP-inhibited 3-5-cyclic phosphodiesterase A
      cyclic GMP inhibited phosphodiesterase A
      Cyclic GMP-inhibited phosphodiesterase A
      EC 3.1.4
      EC 3.1.4.17
      phosphodiesterase 3A, cGMP-inhibited

Background

Phosphodiesterase 3A is a cGMP inhibited, cAMP/cGMP dual-specific phosphodiesterase. PDE3A has been implicated in male erectile dysfunction, mammalian oocyte maturation, platelet function, vascular smooth muscle function, and salivary gland tumors. Three alternatively spliced transcripts have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

AZD5364

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