2333721415607830

PAK4 Antibody (3F10) Summary

    Immunogen
    PAK4 (AAH02921, 68 a.a. ~ 157 a.a) partial recombinant protein with GST tag.KTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGMPEKPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLD
    Specificity
    PAK4 – p21(CDKN1A)-activated kinase 4
    Isotype
    IgG1 Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    PAK4
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        Western Blot 1:500
        ELISA
    Application Notes
    Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PAK4 Antibody (3F10)

      EC 2.7.11
      EC 2.7.11.1
      KIAA1142
      p21 protein (Cdc42/Rac)-activated kinase 4
      p21(CDKN1A)-activated kinase 4
      p21-activated kinase 4
      PAK4
      PAK-4
      protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
      serine/threonine-protein kinase PAK 4

Background

PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : Enolase inhibitors

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