PAK4 Antibody (3F10) Summary
PAK4 (AAH02921, 68 a.a. ~ 157 a.a) partial recombinant protein with GST tag.KTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGMPEKPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLD
PAK4 – p21(CDKN1A)-activated kinase 4
IgG1 Kappa
Monoclonal
Mouse
PAK4
IgG purified
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Applications/Dilutions
- Western Blot 1:500
- ELISA
Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
IgG purified
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PAK4 Antibody (3F10)
- EC 2.7.11
- EC 2.7.11.1
- KIAA1142
- p21 protein (Cdc42/Rac)-activated kinase 4
- p21(CDKN1A)-activated kinase 4
- p21-activated kinase 4
- PAK4
- PAK-4
- protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
- serine/threonine-protein kinase PAK 4
Background
PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : Enolase inhibitors