Nicotinic Acetylcholine R alpha 4/CHRNA4 Antibody (4E3.) Summary
CHRNA4 (NP_000735, 29 a.a. – 128 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. HVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNN
CHRNA4 – cholinergic receptor, nicotinic, alpha 4
IgG1 Kappa
Monoclonal
Mouse
CHRNA4
IgG purified
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Applications/Dilutions
- Western Blot
- ELISA
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
IgG purified
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Nicotinic Acetylcholine R alpha 4/CHRNA4 Antibody (4E3.)
- nAchRa4
- BFNC
- cholinergic receptor, nicotinic, alpha 4
- cholinergic receptor, nicotinic, alpha polypeptide 4
- CHRNA4
- EBN
- EBN1
- ENFL1
- FLJ95812
- nAChR alpha 4
- NACHR
- NACHRA4
- NACRA4
- neuronal acetylcholine receptor subunit alpha-4
- neuronal nicotinic acetylcholine receptor alpha-4 subunit
- Nicotinic Acetylcholine R alpha 4
- Nicotinic Acetylcholine Ra4
Background
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.