NF2/Merlin Antibody Pair Summary
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
- Antibody pair for IP: rabbit polyclonal anti-NF2 (300 ul)
- Antibody pair for WB: mouse polyclonal anti-NF2 (50 ul)
Plasma Membrane Marker
Polyclonal
NF2
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
No Preservative
Notes
Quality control test: Immunoprecipitation-Western Blot (IP-WB).
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for NF2/Merlin Antibody Pair
- ACN
- BANF
- Merlin
- moesin-ezrin-radixin like
- Moesin-ezrin-radixin-like protein
- moesin-ezrin-radizin-like protein
- neurofibromin 2 (bilateral acoustic neuroma)
- neurofibromin 2 (merlin)
- neurofibromin-2
- NF2
- SCH
- Schwannomerlin
- Schwannomin
Background
Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin. Merlin is closely related to the ERM (ezrin, radixin, moesin) family of proteins. The precise funtion of Merlin is not clear. It is thought to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals. It has been implicated in cell proliferation and cellular motility. Mutations in the NF2 gene cause neurofibromatosis type II, a condition characterised by the development of tumors in the central nervous system.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.