Myocilin Antibody Summary
Synthetic peptide from human MYOC.
KLH conjugated synthetic peptide comprising amino acids 69 – 85 [SVIHNLQRDSSTQRLDL] of the human myocilin (MYOC) protein.
Primate (100%), Monkey (94%). Backed by our 100% Guarantee.
IgG
Polyclonal
Rabbit
MYOC
Protein G purified
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Applications/Dilutions
- ELISA 1:1000
- Immunohistochemistry-Paraffin 5 ug/ml
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (100%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.09% Sodium Azide
1 mg/ml
Protein G purified
Alternate Names for Myocilin Antibody
- GLC1A
- GLC1Amyocilin
- GPOA
- JOAG
- JOAG1
- MYOC
- Myocilin
- myocilin, trabecular meshwork inducible glucocorticoid response
- TIGR
- TIGRmutated trabecular meshwork-induced glucocorticoid response protein
- Trabecular meshwork-induced glucocorticoid response protein
Background
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.