Musashi-2 Antibody (960121) [Alexa Fluor® 405] Summary
E. coli-derived recombinant human Musashi-2
Met1-His328
Accession # Q96DH6
Met1-His328
Accession # Q96DH6
Detects human Musashi-2 in direct ELISAs.
IgG2b
Monoclonal
Mouse
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Applications/Dilutions
- Flow Cytometry 0.25-1 ug/10^6 cells
Packaging, Storage & Formulations
Store the unopened product at 2 – 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Musashi-2 Antibody (960121) [Alexa Fluor® 405]
- FLJ36569
- MGC3245
- MSI2
- MSI2H
- musashi homolog 2 (Drosophila)
- Musashi2
- Musashi-2
- RNA-binding protein Musashi homolog 2
Background
Musashi-2 belongs to the evolutionarily conserved Musashi family of RNAbinding proteins which are involved in the translational control oftheir target mRNAs. Musashi-2 has two tandem RNA-recognition domains(RRM-1 and RRM-2) that have the highly conserved RNP(ribonucleoprotein) motifs. By alternative splicing, at least threeMusashi-2 isoforms exist. In mammalian nervous system, Musashi-1 and –2are selectively expressed in neural progenitor cells and play importantroles in maintenance of the stem cell fate. Human Musashi-2 shares 95%amino acid sequence homology with mouse Musashi-2 and 80% amino acidsequence identity with human Musashi-1. Translocations resulting in theformation of Musashi-2/HOXA9 fusion protein is associated withprogression of chronic myelogenous leukemia to the accelerated phaseand blast crisis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.