srep28131

MMP-16/MT3-MMP Antibody [Biotin] Summary

    Immunogen
    The antiserum was produced against synthesized peptide derived from human MMP-16. The immunogen region is: C-terminal.
    Specificity
    MMP-16 Antibody detects endogenous levels of total MMP-16 protein.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    MMP16
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Western Blot
        ELISA
        Immunocytochemistry/Immunofluorescence
        Immunohistochemistry
        Immunohistochemistry-Paraffin
    Readout System
        Streptavidin Full length Protein
        Streptavidin Native Protein
        Streptavidin Native Protein

Reactivity Notes

Human,Mouse, Rat

Packaging, Storage & Formulations

    Storage
    Store at 4C in the dark.
    Buffer
    PBS
    Preservative
    0.05% Sodium Azide
    Purity
    Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MMP-16/MT3-MMP Antibody [Biotin]

      chromosome 8 open reading frame 57
      DKFZp761D112
      EC 3.4.24
      EC 3.4.24.-
      EC 3.4.24.80
      matrix metallopeptidase 16 (membrane-inserted)
      matrix metalloproteinase 16 (membrane-inserted)
      matrix metalloproteinase-16
      Membrane-type matrix metalloproteinase 3
      Membrane-type-3 matrix metalloproteinase
      MMP16
      MMP-16
      MMPX2
      MMP-X2
      MT3MMP
      MT3-MMP
      MT3-MMPC8orf57
      MT-MMP 3
      MT-MMP2
      MTMMP3
      MT-MMP3
      Putative transmembrane protein C8orf57

Background

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : NF-(kappa)B inhibitors

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