MHC Class I H-2Kd Antibody (K3) Summary
Made to Mouse MHC CLASS I H-2Kd
Recognizes the MHC Class I Kd determinant, expressed by all nucleated cells in Kd positive mouse strains.
IgM
Monoclonal
Mouse
HLA-E
Tissue culture supernatant
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
Applications/Dilutions
- Flow Cytometry 1:10-1:1000
Reactivity Notes
Reacts with Mouse. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
No buffer
0.09% Sodium Azide
Tissue culture supernatant
Alternate Names for MHC Class I H-2Kd Antibody (K3)
- DKFZp686P19218
- EA1.2
- EA2.1
- HLA class I histocompatibility antigen, alpha chain E
- HLA class I histocompatibility antigen, E alpha chain
- HLA-6.2
- HLAE
- lymphocyte antigen
- major histocompatibility complex, class I, E
- MHC class I antigen E
- MHC HLA-E alpha-1
- MHC HLA-E alpha-2.1
- MHC
- QA1
Background
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.