MED23 Antibody (4H6) Summary
CRSP3 (NP_004821, 531 a.a. ~ 631 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.LTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTL
CRSP3 – cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa (4H6)
IgG2a Kappa
Monoclonal
Mouse
MED23
IgG purified
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Applications/Dilutions
- ELISA
This product is useful for ELISA.
Reactivity Notes
Human.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
IgG purified
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for MED23 Antibody (4H6)
- 130 kDa transcriptional co-activator
- 133 kDa transcriptional co-activator
- CRSP130
- DRIP130DKFZp434H0117
- mediator complex subunit 23CRSP133
- Protein sur-2 homolog
- subunit 3, 130kDa
- Transcriptional coactivator CRSP130
- Vitamin D3 receptor-interacting protein complex 130 kDa component
Background
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.