MCM2 Antibody Summary
Synthetic peptide corresponding to N-terminal of human MCM2 protein.
This product is specific for MCM2
IgG
Polyclonal
Rabbit
MCM2
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin 1:100
Reactivity Notes
This product is specific for Human. Predicted to cross react, based on sequesce homology, with Bovine, Dog, Pig, Rabbit
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
10mM PBS (pH 7.4) and 1.0% BSA
0.1% Sodium Azide
Immunogen affinity purified
Alternate Names for MCM2 Antibody
- BM28
- BM28MGC10606
- CCNL 1
- CCNL1
- cdc19
- CDCL1
- CDCL1mitotin
- D3S3194
- EC 3.6.4.12
- KIAA0030MITOTIN
- MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
- MCM2
- minichromosome maintenance complex component 2
- minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin)
- minichromosome maintenance deficient 2 (mitotin)
- Mitotin
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.