Leptin/OB Antibody (M1) Summary
LEP (AAH60830.1, 22 a.a. – 167 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. VPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGLDFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC
Secreted
LEP – leptin (obesity homolog, mouse)
IgG1 Kappa
Monoclonal
Mouse
LEP
IgG purified
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Applications/Dilutions
- ELISA
Antibody reactivity against recombinant protein on ELISA. GST alone used as a negative control.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
IgG purified
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Leptin/OB Antibody (M1)
- FLJ94114
- LEP
- leptin (murine obesity homolog)
- leptin (obesity homolog, mouse)
- Leptin
- OB
- Obese protein
- obese, mouse, homolog of
- Obesity factor
- OBOBS
Background
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets :　Urotensin Receptor inhibitors