Leptin/OB Antibody (9C10) Summary
Recombinant full length protein (Human).
Secreted
Recognizes recombinant human leptin and leptin circulating in human blood.
IgG1
Monoclonal
Mouse
LEP
Protein A purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions
- Western Blot 1:100-1:2000
- Sandwich ELISA 1:100-1:2000
Recommended pairs for sandwich immunoassay (capture-detection): NB110-8268 – NB110-8271
Reactivity Notes
Not yet tested in other species, but may be cross reactive to mouse and rat due to 85% and 84% identity to human leptin respectively.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (pH 7.4)
0.9% Sodium Azide
Protein A purified
Alternate Names for Leptin/OB Antibody (9C10)
- FLJ94114
- LEP
- leptin (murine obesity homolog)
- leptin (obesity homolog, mouse)
- Leptin
- OB
- Obese protein
- obese, mouse, homolog of
- Obesity factor
- OBOBS
Background
Leptin, the product of the ob (obese) gene, is a 16 kDa protein consisting of 146 amino acid residues. Leptin is produced in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and regulation of body weight. It targets the central nervous system, particularly hypothalamus, affecting food intake. Leptin levels are high in most obese individuals. Studies have shown that it may also influence reproductive function.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : Mps1 inhibitors