fonc.2015.00282

LSD1 Antibody Summary

    Immunogen
    In vivo generated recombinant protein fragment.
    Localization
    Nucleus (By similarity).
    Marker
    Nucleus Marker
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    KDM1A
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Western Blot 1:100-1:2000
        Chromatin Immunoprecipitation 1:10-1:500
        ELISA 1:100-1:2000
    Application Notes
    QC tested by ELISA using a recombinant protein. ChIP works in animal number Q3430 only.

Reactivity Notes

Drosophila

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
    Preservative
    No Preservative
    Concentration
    1 mg/ml
    Purity
    Immunogen affinity purified

Notes

The following lot numbers are currently available: G3131-072A01 Animal Number: Q3429 Lot: G3131-072A02 Animal Number: Q3430

Alternate Names for LSD1 Antibody

      amine oxidase (flavin containing) domain 2
      AOF2
      AOF2lysine-specific histone demethylase 1
      BHC110
      BHC110FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit
      Flavin-containing amine oxidase domain-containing protein 2
      KIAA0601KDM1
      LSD1
      LSD1BRAF35-HDAC complex protein BHC110
      lysine (K)-specific demethylase 1
      Lysine (K)specific Demethylase 1A
      Lysine (K)-specific Demethylase 1A
      lysine-specific histone demethylase 1A

Background

Probable histone demethylase that specifically demethylates Lys-4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that iflavin monoamine oxidase family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

USP7/USP48 inhibitor

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