LASS1 Antibody (2E8) Summary

wjh.v7.i19.2202

LASS1 Antibody (2E8) Summary

    Immunogen
    LASS1 (NP_067090, 301 a.a. ~ 351 a.a) partial recombinant protein with GST tag.YIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAEKPLRNGLVKDKRF
    Localization
    Endoplasmic reticulum membrane; Multi-pass membrane protein
    Specificity
    LASS1 – LAG1 longevity assurance homolog 1 (S. cerevisiae)
    Isotype
    IgG2a Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    CERS1
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        Western Blot 1:500
        ELISA
    Application Notes
    Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for LASS1 Antibody (2E8)

      CerS1
      LAG1 homolog, ceramide synthase 1
      LAG1 longevity assurance homolog 1
      LAG1MGC90349
      longevity assurance (LAG1, S. cerevisiae) homolog 1
      Longevity assurance gene 1 protein homolog 1
      Protein UOG-1
      UOG1LAG1 longevity assurance homolog 1 (S. cerevisiae)
      upstream of GDF1

Background

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FG-4594