L-Selectin/CD62L Antibody (LT-TD180) Summary
Peripheral blood leukocytes
Cell Membrane
The antibody LT-TD180 reacts with CD62L (L-selectin), a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.
IgG1
Monoclonal
Mouse
SELL
Ion exchange chromatography
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Applications/Dilutions
- Flow Cytometry 1:10-1:1000
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (pH 7.4)
15mM Sodium Azide
1.0 mg/ml
Ion exchange chromatography
Alternate Names for L-Selectin/CD62L Antibody (LT-TD180)
- CD62L antigen
- CD62L
- gp90-MEL
- hLHRc
- LAM1
- LAM-1
- LAM1LECAM1
- LECAM1
- LEU8
- Leu-8
- Leukocyte adhesion molecule 1
- Leukocyte surface antigen Leu-8
- Leukocyte-endothelial cell adhesion molecule 1
- LNHR
- LNHRTQ1
- LSEL
- L-Selectin
- LYAM1
- Lyam-1
- LYAM1CD62 antigen-like family member L
- Lymph node homing receptor
- lymphocyte adhesion molecule 1
- pln homing receptor
- PLNHR
- selectin L
- SELL
- TQ1
Background
CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.