ijhpm.2016.42

KIR2DS5/CD158g Antibody (1165A) [Alexa Fluor® 405] Summary

    Additional Information
    Recombinant Monoclonal Antibody.
    Immunogen
    NS0 mouse myeloma cell line transfected with human KIR2DS5/CD158g
    His22-His245
    Accession # Q14953
    Specificity
    Detects human KIR2DS5/CD158g in direct ELISAs.
    Isotype
    IgG
    Clonality
    Monoclonal
    Host
    Rabbit
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Applications/Dilutions

    Dilutions
        Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Store the unopened product at 2 – 8 °C. Do not use past expiration date.
    Buffer
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KIR2DS5/CD158g Antibody (1165A) [Alexa Fluor® 405]

      killer cell immunoglobulin-like receptor 2DS5
      CD158g
      killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
      KIR2DS5
      NKAT9

Background

Killer-immunoglobulin-like receptors (KIR) are polymorphous activating and inhibitory receptors expressed on the surface of NK cells and some T cells. KIR genes are highly homologous. KIR proteins expressing the long (L) cytoplasmic domain are inhibitory, while KIRs with short (S) cytoplasmic domains are activating. Thus, KIR2DS5 is an activating receptor for NK cells, and is thought to play a role in NK cell function in response to a number of conditions. While many KIR proteins bind HLA-class I molecules, the ligand(s) for KIR2DS5 remain unknown.  

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

AZD-3474

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