KIR2DS1/CD158h Antibody (1127B) [Alexa Fluor® 405] Summary
Recombinant Monoclonal Antibody.
HEK293 human embryonic kidney cell line transfected with human KIR2DS1/CD158h
Met1-His245
Accession # Q14954
Met1-His245
Accession # Q14954
Detects human KIR2DS1/CD158h in flow cytometry. Clone 1127B recognizes KIR2DS1 and some alleles of KIR2DL1, both members of the killer cell immunoglobulin-like receptor (KIR) family. Because Clone 1127B displays partial cross-reactivity with KIR2DL1, co-staining with Mouse Anti-Human KIR2DL1 Clone 143211 (Catalog # FAB1844F) is recommended.
IgG
Monoclonal
Rabbit
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
Applications/Dilutions
- Flow Cytometry 0.25-1 ug/10^6 cells
Packaging, Storage & Formulations
Store the unopened product at 2 – 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for KIR2DS1/CD158h Antibody (1127B) [Alexa Fluor® 405]
- killer cell immunoglobulin-like receptor 2DS1
- CD158a
- CD158h
- EB6ActI
- killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
- KIR2DS1
- p50.1
Background
The KIRs comprise a family of 14 polymorphic and homologousactivating and inhibitory receptors expressed primarily on CD56dimNK cells. KIR2DS1 is an activating receptor with high homology to theinhibitory receptor KIR2DL1. Both KIR2DL1 and KIR2DS1 bind to HLA-C allelescontaining the C2 epitope. KIR2DS1 and KIR2DL1 expression regulates NK celllicensing and activation in a number of immune contexts.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.