Jak3 Antibody (452524) [Alexa Fluor® 405] Summary
E. coli-derived recombinant human Jak3
Gly46-Thr209
Accession # P52333
Gly46-Thr209
Accession # P52333
Detects human Jak3 in direct ELISAs.
IgG2b
Monoclonal
Mouse
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
Applications/Dilutions
- Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells
Packaging, Storage & Formulations
Store the unopened product at 2 – 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Jak3 Antibody (452524) [Alexa Fluor® 405]
- EC 2.7.10
- Jak3
- JAK3_HUMAN
- JAK-3EC 2.7.10.2
- JAKL
- JAKLtyrosine-protein kinase JAK3
- Janus kinase 3Leukocyte janus kinase
- LJAK
- L-JAKJanus kinase 3 (a protein tyrosine kinase, leukocyte)
Background
Janus Kinase 3 (Jak3) belongs to the Jak family of protein tyrosine kinases that couple to cytokine receptors and are activated by ligand binding to these receptors. Also known as Leukocyte Janus Kinase (LJak), Jak3 is activated after binding to the gamma chain of Interleukin receptors, specifically the IL-2 and IL-4 receptors. Activation of Jak3 is associated with the rapid tyrosine phosphorylation of STAT proteins. Defects in Jak3 cause an autosomal severe combined immunodeficiency disease (SCID).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : CRISPR_Cas20 inhibitors