genetics.115.181099

Jagged 1 Antibody (1B7) Summary

    Immunogen
    JAG1 (NP_000205 905 a.a. – 1014 a.a.) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. HKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYSIYIACEPSPSANNEIHV
    Specificity
    JAG1 (1B7)
    Isotype
    IgG2b Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    JAG1
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        Western Blot
        ELISA
    Application Notes
    Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Jagged 1 Antibody (1B7)

      AGS
      AHDMGC104644
      Alagille syndrome
      AWS
      CD339 antigen
      CD339
      HJ1
      JAG1
      Jagged 1
      Jagged1
      JAGL1
      protein jagged-1

Background

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

AR-C155860

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