journal.pone.0142750

Integrin alpha 2b/CD41 Antibody (IVA30) [DyLight 755] Summary

    Immunogen
    Bovine trombocytes.
    Specificity
    The antibody IVA30 reacts with CD41/CD61 complex (bovine), one of the earliest markers of the megakaryocytic lineage. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes; the complex may be absent or strongly reduced in Glanzmanns thrombasthenia (GT).
    Isotype
    IgG2
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    ITGA2B
    Purity
    Protein A purified
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Applications/Dilutions

    Dilutions
        ELISA
        Flow Cytometry

Packaging, Storage & Formulations

    Storage
    Store at 4C in the dark.
    Buffer
    50mM Sodium Borate
    Preservative
    0.05% Sodium Azide
    Purity
    Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Integrin alpha 2b/CD41 Antibody (IVA30) [DyLight 755]

      CD41 antigen
      CD41
      CD41BHPA3
      GP2B
      GP2Bintegrin alpha-IIb
      GPalpha IIb
      GPIIb
      GTA
      HPA3
      Integrin alpha 2b
      integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41)
      integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B)
      ITGA2b
      ITGAB
      platelet fibrinogen receptor, alpha subunit
      Platelet membrane glycoprotein IIb
      platelet-specific antigen BAK

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

MLN4925

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