IL-9 R Antibody (AH9R7) Summary
Human CD129-transfected cell line
The mouse monoclonal antibody AH9R7 recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells andneurons.
IgG2b
Monoclonal
Mouse
IL9R
Protein A purified
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Applications/Dilutions
- Blocking/Neutralizing
- ELISA
- Flow Cytometry
- CyTOF-ready
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (approx. pH 7.0)
No Preservative
1 mg/ml
Protein A purified
Alternate Names for IL-9 R Antibody (AH9R7)
- CD129 antigen
- CD129
- IL-9 R
- IL-9 receptor
- IL9R
- IL-9R
- interleukin 9 receptor
- interleukin-9 receptor
Background
CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets :　Toll-like Receptor (TLR) inhibitors