IL-2 R beta Antibody (L316) Summary
Rat CRNK cells and rat IL-2R beta cDNA-transfected mouse L929 cell line.
Cell Membrane
NB100-63377 The interleukin-2 receptor (IL-2R) is composed of three subunits, namely alpha, beta and gamma. NB100-63377 recognizes CD122 the 80kD Beta subunit of IL-2R, which is shared by the IL-15 receptor. In peripheral lymphoid tissues of adult rats, CD122 is primarily expressed by NK cells and a subset of T lymphocytes.
IgG1
Monoclonal
Mouse
IL2RB
Protein G purified
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Applications/Dilutions
- Flow Cytometry 1:10-1:1000
Reactivity Notes
Reacts with Rat.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.4)
0.09% Sodium Azide
1.0 mg/ml
Protein G purified
Alternate Names for IL-2 R beta Antibody (L316)
- CD122 antigen
- CD122
- high affinity IL-2 receptor beta subunit
- High affinity IL-2 receptor subunit beta
- IL-15 R beta
- IL-2 R beta
- IL-2 receptor subunit beta
- IL2R beta
- IL-2R subunit beta
- IL2RB
- IL-2Rb
- interleukin 15 receptor, beta
- interleukin 2 receptor, beta
- interleukin-2 receptor subunit beta
- P70-75
- p75
Background
IL2 Receptor beta (CD122) is a member of the immunoglobulin superfamily that forms the high affinity IL2 receptor with CD25 and CD132. This receptor chain, which is also shared by the IL15 receptor, is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL2 Receptor beta chain can combine with either the common gamma subunit (gamma c) alone or the gamma c subunit and the IL2 Receptor alpha subunit to generate intermediate or high affinity IL2 receptor complexes, respectively. CD122 levels can be upregulated by activation stimuli such as IL2.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.