IL-2 Antibody (MQ1-17H12) [FITC] Summary
Made to Human IL-2
Secreted
Recognises human interleukin-2 (IL-2) and may be used to detect intracellular IL-2 in flow cytometric techniques.
IgG2a
Monoclonal
Rat
IL2
Protein A or G purified
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Applications/Dilutions
- Flow Cytometry Neat-1:10
Reactivity Notes
Reacts with Human. Cross reacts with Cynomolgus monkey.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.4)
0.09% Sodium Azide
0.1 mg/ml
Protein A or G purified
Alternate Names for IL-2 Antibody (MQ1-17H12) [FITC]
- aldesleukin
- IL2
- IL-2
- IL-2lymphokine
- interleukin 2
- interleukin-2
- involved in regulation of T-cell clonal expansion
- T cell growth factor
- T-cell growth factor
- TCGF
Background
Human interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL-2 has been shown to have anti tumor effects in some studies. This is probably mediated by cytotoxic effector cells.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.