journal.pone.0174276

IL-1 RI Antibody (JAMA-147) [DyLight 488] Summary

    Immunogen
    Extracellular domain of murine IL-1R.
    Specificity
    NB100-65865 recognizes murine CD121a, which is the 80kD type I interleukin-1 receptor. CD121a is weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts. The ligands for CD121a are the interleukin-1 (IL-1) family members; IL-1 alpha; IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a. Clone JAMA-147 has been reported to block IL-1 dependent cellular responses. (1).
    Isotype
    IgG
    Clonality
    Monoclonal
    Host
    Armenian Hamster
    Gene
    IL1R1
    Purity
    Protein G purified
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Applications/Dilutions

    Dilutions
        Flow Cytometry

Reactivity Notes

Reacts with Mouse.

Packaging, Storage & Formulations

    Storage
    Store at 4C in the dark.
    Buffer
    50mM Sodium Borate
    Preservative
    0.05% Sodium Azide
    Purity
    Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IL-1 RI Antibody (JAMA-147) [DyLight 488]

      CD121 antigen-like family member A
      CD121a antigen
      CD121a
      IL-1 RI
      IL1R
      IL1R1
      IL1RI
      IL-1RI
      IL1RT1
      IL-1RT1
      IL-1RT-1
      Interleukin 1 Receptor 1
      interleukin 1 receptor, type I
      interleukin receptor 1
      interleukin-1 receptor type 1
      p80

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : JAK inhibitors

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