IL-1 RI Antibody (JAMA-147) [Alexa Fluor® 405] Summary
Extracellular domain of murine IL-1R.
NB100-65865 recognizes murine CD121a, which is the 80kD type I interleukin-1 receptor. CD121a is weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts. The ligands for CD121a are the interleukin-1 (IL-1) family members; IL-1 alpha; IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a. Clone JAMA-147 has been reported to block IL-1 dependent cellular responses. (1).
IgG
Monoclonal
Armenian Hamster
IL1R1
Protein G purified
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Applications/Dilutions
- Flow Cytometry
Reactivity Notes
Reacts with Mouse.
Packaging, Storage & Formulations
Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Protein G purified
Notes
Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or [email protected]. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for IL-1 RI Antibody (JAMA-147) [Alexa Fluor® 405]
- CD121 antigen-like family member A
- CD121a antigen
- CD121a
- IL-1 RI
- IL1R
- IL1R1
- IL1RI
- IL-1RI
- IL1RT1
- IL-1RT1
- IL-1RT-1
- Interleukin 1 Receptor 1
- interleukin 1 receptor, type I
- interleukin receptor 1
- interleukin-1 receptor type 1
- p80
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets :　Bacterial inhibitors